Governor's Conference 2018

THE GOVERNOR'S CONFERENCE
ON EFFECTIVE PARTNERING IN CANCER RESEARCH
The Role of p53 in Li-Fraumeni Syndrome

Wolfensohn Hall, Institute for Advanced Study

APRIL 19, 2018

8:55 am - 9:00 am WELCOMING REMARKS
9:00 am - 10:00 am Shelley L. Berger
University of Pennsylvania

Epigenetic pathways in cancer and in cancer
immunotherapy
10:00 am - 11:00 am

Chang S. Chan
Rutgers Cancer Institute of New Jersey
Tumorigenesis and penetrance in Li-Fraumeni
Syndrome
11:00 am - 11:30 am BREAK - Bloomberg Hall Biology Atrium
11:30 am - 12:30 pm Hugues de Thé
Collège de France

P53-driven acute promyelocytic leukemia cure by
retinoic acid and arsenic
12:30 pm - 2:00 pm LUNCH - Available in Institute Dining Hall
2:00 pm - 3:00 pm Pierre Hainaut
Institute for Advanced Biosciences
Inserm/CNRS/UGA

Lifetime control of p53 function: walking the
ridge trail between degenerative diseases and
cancer
3:00 pm - 3:30 pm AFTERNOON TEA - Fuld Hall Common Room
3:30 pm - 4:30 pm David Malkin
The Hospital for Sick Children

Early Detection and Prevention of Cancer in
Li-Fraumeni Syndrome: A Multi-Pronged
Approach
4:30 pm - 5:30 pm Gerard P. Zambetti
St. Jude Children's Research Hospital

The hypomorphic Brazilian mutant TP53-R337H
and variable tumor susceptibility: Identification
of a potential genetic modifier